Hizentra Patient Counseling Information

Instructions for use: Follow the steps as follows and use aseptic technique to administer Hizentra.
1. Clean surface: Thoroughly clean a table or other flat surface using an antiseptic wipe.
2. Assemble supplies: Place Hizentra and other supplies and equipment needed for the infusion on a clean, flat surface.
3. Thoroughly wash and dry hands.
4. Check Vials: Visually inspect Hizentra for particles in the solution or discoloration as well as expiry date before administering Hizentra. Do not use solutions that are cloudy or contain particles. Do not use solutions that have been frozen. Administer solution which is at room or body temperature.
Once a vial has been opened, use the solution immediately.
5. Preparation of Hizentra for infusion: Clean the vial stopper - Remove the protective cap from the vial to expose the central portion of the rubber stopper. Clean the stopper with an alcohol wipe or antiseptic preparation and allow it to dry.
Transfer Hizentra to syringe for infusion - Attach a transfer device or needle to a sterile syringe, using aseptic technique. If using a transfer device (vented spike), follow the instructions provided by the device manufacturer. If using a needle, pull back on the plunger to draw air into the syringe that is comparable to the amount of Hizentra to be withdrawn. Then, insert the needle into the center of the vial stopper and, to avoid foaming, inject air into headspace of the vial (not into the liquid).
Finally, withdraw the desired volume of Hizentra. When using multiple vials to achieve the desired dose, repeat this step.
6. Prepare the tubing: Attach the administration tubing or needle set to the syringe. Prime the tubing to eliminate all remaining air.
7. Prepare infusion site(s): Select the infusion site(s) - The number and location of injection sites depends on the volume of the total dose. Each infusion site should be at least 5 cm apart. You may use an unlimited number of sites simultaneously.
Clean the infuson site(s) using an antiseptic skin preparation, Allow each site to dry before proceeding.
8. Insert the needle: Grasp the skin between 2 fingers and insert the needle into the subcutaneous tissue.
Secure the needle to the skin - If necessary, use gauze and tape or transparent dressing to hold the needle in place.
9. Infuse Hizentra: Start infusion. If using an infusion pump, follow the manufacturer's instructions.
10. Record the infusion: Record the following data in your treatment diary: the date of administration, the batch number of the medicine, and the infused volume, flow rate, the number and location of infusion sites.
11. Clean up: Discard any unused product and all used administration supplies after administration in accordance with local requirements.
If you have any further questions on the use of this medicine, ask your doctor or healthcare profession.