Hemabate Contraindications

Hypersensitivity (including anaphylaxis and angioedema) to HEMABATE Sterile Solution [see Post-marketing experience under Adverse Reactions].
Acute pelvic inflammatory disease.
Patients with active cardiac, pulmonary, renal or hepatic disease.
HEMABATE does not appear to directly affect the fetoplacental unit. Therefore, the possibility does exist that the previable fetus aborted by HEMABATE could exhibit transient life signs. HEMABATE is not indicated if the fetus in utero has reached the stage of viability. HEMABATE should not be considered a feticidal agent.
Evidence from animal studies has suggested that certain other prostaglandins have some teratogenic potential. Although these studies do not indicate that HEMABATE is teratogenic, any pregnancy termination with HEMABATE that fails should be completed by some other means.
This product contains benzyl alcohol. Benzyl alcohol has been reported to be associated with a fatal "Gasping Syndrome" in premature infants.