The most frequently reported adverse drug reactions (ADRs) of Iron Sucrose were transient taste perversion, hypotension, fever and shivering, injection site reactions and nausea. Non-serious anaphylactoid reactions occurred rarely.
In general anaphylactoid reactions are potentially the most serious adverse reactions.
Nervous system disorders: Common: transient taste perversions (in particular metallic taste). Uncommon: headache, dizziness. Rare: paraesthesia, syncope, loss of consciousness, burning sensation.
Cardio-vascular disorders: Uncommon: hypotension and collapse, tachycardia and palpitations. Rare: hypertension.
Respiratory, thoracic and mediastinal disorders: Uncommon: bronchospasm, dyspnoea.
Gastrointestinal disorders: Uncommon: nausea; vomiting, abdominal pain, diarrhoea.
Skin and subcutaneous tissue disorders: Uncommon: pruritus, urticaria, rash, exanthema, erythema.
Musculoskeletal, connective tissue and bone disorders: Uncommon: muscle cramps, myalgia.
General disorders and administration site disorders: Uncommon: fever, shivering, flushing, chest pain and tightness. Injection site disorders such as superficial phlebitis, burning, swelling. Rare: arthralgia, peripheral oedema, fatigue, asthenia, malaise, feeling hot, oedema.
Immune system disorders: Rare: anaphylactoid reactions.
Moreover, in spontaneous reports the following adverse reactions have been reported: Isolated cases: reduced level of consciousness, light-headed feeling, confusion, angio-oedema, swelling of joints, hyperhidrosis, back pain, bradycardia, chromaturia.