Enablex Dosage/Direction for Use

Adults: The recommended starting dose is 7.5mg daily. For those patients requiring greater symptom relief, the dose may be increased to 15mg daily as early as two weeks after starting therapy, based on individual response.
Geriatric patients: No dose adjustment is required in elderly patients (see PHARMACOLOGY under Actions).
Paediatric patients: No studies have been performed in children. Therefore, until more information is available, Enablex is not recommended for use in children.
Renal impairment: No dose adjustment is required in patients with impaired renal function (see PHARMACOLOGY under Actions).
Hepatic impairment: There is a risk of increased exposure in this population (see PHARMACOLOGY), however, no dose adjustment is required in patients with mild hepatic impairment (Child Pugh A). The daily dose of Enablex should not exceed 7.5 mg in patients with moderate hepatic impairment (Child Pugh B).
Enablex is not recommended for use in patients with severe hepatic impairment (Child Pugh C).
Method of Administration: Enablex prolonged-release tablets should be taken once daily with liquid. They may be taken with or without food, and should be swallowed whole and not chewed, divided or crushed.