Dymista Dosage/Direction for Use

Dosage: Adults and adolescents (e.g. 12 years and older): One spray in each nostril twice daily (morning and evening).
Children below 12 years: DYMISTA nasal spray is not recommended for use in children below 12 years of age as safety and efficacy has not been established in this age group.
Elderly: No dose adjustment is required in this population (see Pharmacology: Pharmacokinetics: Special Populations: Age under Actions and Use in Elderly under Precautions).
Renal and hepatic impairment: No dose adjustment is required in patients with renal impairment or mild to moderate hepatic impairment (see Pharmacology: Pharmacokinetics: Special Populations: Renal Impairment under Actions and Use in Renal Impairment under Precautions).
There are no data in patients with severe hepatic impairment (see Pharmacology: Pharmacokinetics: Special Populations: Hepatic Impairment under Actions and Use in Hepatic Impairment under Precautions).
Duration of treatment: DYMISTA nasal spray is suitable for long-term use. There is no restriction regarding duration of use.
Method of Administration: Dymista Nasal Spray is for administration by the nasal route only.
Preparing the spray: Shake the bottle gently before each use. Then, remove the protective cap.
Prior to first use, DYMISTA nasal spray must be primed by pressing down and releasing the pump 6 times until a fine mist appears. If DYMISTA nasal spray has not been used for more than 7 days, reprime by pressing down and releasing the pump a number of times until a fine mist is produced.
Using the spray: After blowing the nose, spray the suspension once into each nostril keeping the head tilted downward. After each use, wipe the spray tip and replace the protective cap.