The most commonly observed adverse events associated with the use of Cipram and not seen at an equal incidence among placebo-treated patients were: Dry mouth, nausea, somnolence, increased sweating and tremor. The incidence of each in excess over placebo is low (<10%).
In comparative clinical trials with tricyclic antidepressants, the incidence of adverse events occurring with Cipram was found to be lower in all cases.
In exceptional cases, seizures have occurred. Cipram may cause a small reduction in heart rate which normally is without clinical importance. However, in patients with preexisting low heart rate this may lead to bradycardia.
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