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Patients suffering from active peptic ulceration or haemophilia or known to be allergic to aspirin.
Use in pregnancy: There is clinical and epidemiological evidence of the safety of aspirin in pregnancy, but it may prolong labour and contribute to maternal and neonatal bleeding and is best avoided in the last trimester of pregnancy.
Use in children: Not recommended.
Use in the elderly: Elderly patients do not tolerate aspirin as well as younger patients. They may experience tinnitus, nausea, anorexia and gastrointestinal irritation though this would be less likely at the doses recommended for antiplatelet action.
