Cancidas Description

Before reconstitution, CANCIDAS appears to be solid, white to off-white compact powder.
After reconstitution, CANCIDAS appears to be a clear, colorless solution, leaving no visible residue as undissolved matter and free from particles of foreign matter that can be observed on visual inspection.
Therapeutic Class: CANCIDAS is a sterile, lyophilized product for intravenous infusion that contains a semi-synthetic lipopeptide (echinocandin) compound synthesized from a fermentation product of Glarea lozoyensis. CANCIDAS is the first of a new class of antifungal drugs (echinocandins) that inhibit the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall.
CANCIDAS (caspofungin acetate) is 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N²-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B₀ diacetate (salt).
Caspofungin acetate is a hygroscopic, white to off-white powder. It is freely soluble in water and methanol, and slightly soluble in ethanol. The pH of a saturated aqueous solution of caspofungin acetate is approximately 6.6. The empirical formula is C₅₂H₈₈N₁₀O₁₅·2C₂H₄O₂ and the formula weight is 1213.42.
Excipients/Inactive Ingredients: In addition to the active ingredient caspofungin acetate, CANCIDAS contains the following inactive ingredients: sucrose, mannitol, acetic acid, and sodium hydroxide.