View Avoral overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Dissolve in 200 mL water.
Contraindications
Hypernatremia, metabolic or resp alkalosis, hypocalcaemia, hypochlorhydria, Addison's disease, acute dehydration, heat cramps, overt & occult cardiac failure, severe myocardial damage. Not recommended in concomitant use w/ hexamine mandelate or hippurate therapy. Avoid concomitant use w/ quinolone antibiotics. Severe renal impairment or renal failure.
Not to be taken by patients on Na restricted diet. Peptic ulceration; heart failure, oedema, HTN, eclampsia &/or aldosteronism. Renal abnormalities &/or impairment. Pregnancy & lactation.
Decreased therapeutic effect of chlorpropamide, lithium, salicylates, tetracyclines. Increased therapeutic effect of amphetamines, ephedrine, pseudoephedrine. Promoted development of Ca stones & hypernatremia w/ antacids. Increased Al absorption w/ Al-containing antacids w/ salts. Reduced urine solubility of ciprofloxacin, norfloxacin or ofloxacin.
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