Discontinue use if anaphylactic, other severe hypersensitivity or infusion reactions occur. Acute febrile or resp illness; pre-existing upper airway obstruction; patients susceptible to fluid overload, w/ acute underlying resp illness or compromised cardiac &/or resp function. Immunogenicity. Pretreatment w/ antihistamine, antipyretics or both 60 min prior to infusion & evaluate airway patency prior to treatment initiation. Concomitant use w/ epinephrine. Pregnancy & lactation. Elderly ≥65 yr.
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