Stomatitis, diarrhea, abdominal pain, nausea, vomiting, constipation, dry mouth; fatigue/malaise, general & peripheral edema, pyrexia, asthenia, fever, mucosal inflammation; infections, nasopharyngitis/rhinitis/upper resp infection, UTI, gastroenteritis, streptococcal pharyngitis; wt loss; decreased appetite, hyperglycemia, DM; arthralgia, back pain, pain in extremity, muscle spasms; dysgeusia, headache/migraine, dizziness; insomnia; cough/productive cough, dyspnea/exertional dyspnea, epistaxis, pneumonitis, oropharyngeal pain; rash, pruritus/generalized pruritus, alopecia, nail disorders, dry skin/xeroderma, acne; hot flush, HTN; anxiety, aggression or other behavioral disturbance; anemia, leukopenia, thrombocytopenia, lymphopenia, neutropenia, elevated partial thromboplastin time, hypercholesterolemia, hyperglycemia, increased AST, ALT, creatinine & alkaline phosphatase, hypertriglyceridemia, hypoalbuminemia, hypo- & hyperkalemia, decreased bicarbonate, hypophosphatemia, hypocalcemia, hyponatremia, hyperbilirubinemia.