Symptoms: The most important symptoms of acute levofloxacin overdose are the occurrence of central nervous system disturbances such as confusion, dizziness, consciousness, and convulsions, QT interval elevation and gastrointestinal disturbances such as nausea and mucosal erosion.
Treatment: In case of overdose, symptomatic treatment should be performed. Perform ECG monitoring, because of the possibility of QT intervals prolongation. Antacids can be used to protect gastric mucosa. Hemodialysis including peritoneal dialysis and CAPD is not effective to remove levofloxacin. There is no specific antidote.