250 or 500 mg every 24 hr.
Community-acquired pneumonia 500 mg/24 hr for 7-14 days or 750 mg/24 hr for 5 days.
Nosocomial pneumonia 750 mg/24 hr for 7-14 days.
Acute bacterial sinusitis 500 mg/24 hr for 7-14 days or 750 mg/24 hr for 5 days.
Acute exacerbation of chronic bronchitis 500 mg/24 hr for 7 days or 750 mg/24 hr for 3-5 days.
Chronic bacterial prostatitis 500 mg/24 hr for 28 days.
Complicated skin infections, complicated UTI, acute pyelonephritis 250-750 mg once daily for 7-14 days.
Renal impairment CrCl >50 mL/min 250 mg or 500 mg/24 hr,
CrCl 20-50 mL/min Initially 250 mg followed by 125 mg/24 hr or 500 mg followed by 250 mg/24 hr,
CrCl 10-19 mL/min Initially 250 mg followed by 125 mg/48 hr or 500 mg followed by 125 mg/24 hr,
CrCl <10 mL/min (w/ hemodialysis & CAPD) Initially 250 mg followed by 125 mg/48 hr or 500 mg followed by 125 mg/24 hr.
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