Varivax Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Live attenuated varicella virus (Oka/Merck strain)

Indications/Uses

Vaccination against varicella in individuals ≥12 mth.

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Dosage/Direction for Use

SC Adult & adolescent ≥13 yr 0.5 mL dose at elected date then, a 2nd dose 4-8 wk later. Childn 12 mth to 12 yr 0.5 mL as a single dose.

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Overdosage

View Varivax overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity to any component including gelatin. History of anaphylactoid reaction to neomycin. Blood dyscrasias, leukemia, lymphoma, malignant neoplasms affecting bone marrow or lymphatic system. Immunosuppressive therapy. Primary & acquired immunodeficiency states. Family history of congenital or hereditary immunodeficiency. Active untreated TB, active febrile illness w/ fever >38.5°C. Pregnancy.

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Special Precautions

Do not inject IV. Defer vaccination for at least 5 mth following blood/plasma transfusions or administration of immune globulin or varicella zoster immune globulin (VZIG). Following administration of Varivax, any immune globulin including VZIG should not be given for 2 mth thereafter. Avoid use of salicylates for 6 wk after vaccination. HIV infected young adult & childn w/ & w/o evidence of immunosuppression. Avoid close association w/ high-risk individuals for up to 6 wk. Avoid pregnancy for 3 mth after vaccination. Lactation. Infant <12 mth.

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Use In Pregnancy & Lactation

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Adverse Reactions

Fever, inj site complaints (pain/soreness, swelling, erythema, rash, pruritus, pyrexia, hematoma, induration, stiffness, numbness) varicella-like rash. Anaphylaxis w/ or w/o allergic history including anaphylactic shock & related phenomena eg, angioneurotic, facial & peripheral edema. Nausea, vomiting. Aplastic anemia, thrombocytopenia, lymphadenopathy. Encephalitis, CVA, transverse myelitis, Guillain-Barre syndrome, Bell's palsy, ataxia, febrile & non-febrile seizures, aseptic meningitis, dizziness, paresthesia, irritability. Pharyngitis, pneumonia/pneumonitis, URTI. SJS, erythema multiforme, Henoch-Schonlein purpura, impetigo & cellulitis, herpes zoster. Necrotizing retinitis in immunocompromised individuals.

Drug Interactions

Reye's syndrome w/ salicylates.

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Storage

View Varivax storage conditions for details to ensure optimal shelf-life.

Description

View Varivax description for details of the chemical structure and excipients (inactive components).

Action

View Varivax mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Vaccines, Antisera & Immunologicals

ATC Classification

J07BK01 - varicella, live attenuated ; Belongs to the class of varicella viral vaccines.

Regulatory Classification

Presentation/Packing

Form

Varivax vaccine (inj)

Packing/Price

((vial) 0.5 mL single-dose + 0.7 mL diluent) 1's

Varivax

vaccine, varicella-zoster

Manufacturer:

Merck Sharp & Dohme