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Caution should be observed in treating patients with gout because this drug slight transient increase in serum uric acid level.
Due to slight effect on heart, caution should be given in treating patients with heart disease who is treated with digitalis therapy.
Methisoprinol should not be administered on bacteria infection because they have no antibacterial effect.
Methisoprinol should not be used during first 4 months pregnancy.
It is not known whether Methisoprinol is exerted in human milk.
Considered ratio between therapy to toxic dose is 1:100, Methisoprinol can be used without worried about toxic effect. Accumulation will not appear due to Methisoprinol and its metabolite are rapidly eliminated in the urine.
