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Symptoms of an overdosage will rarely occur, in view of the mode of administration and precautions to be taken.
The acute reactions in case of an overdosage are hypotension, fever, rapid pulse and general symptoms of shock. The treatment is symptomatic with careful monitoring of pulmonary function and haematological parameters.
In respiratory complications the patient should be treated with corticosteroids and broad spectrum antibiotics. Usually the pulmonary reactions to an overdose (fibrosis) are not reversible unless they are identified early.
