It is recommended that in patients with renal impairment, mesalazine should be used with caution and only after a careful evaluation of the potential benefit against risk of treatment.
Use in pregnancy & lactation: Animal studies on oral mesalazine do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/foetal development, parturition or postnatal development. Salofalk should only be used during pregnancy if the potential benefit outweighs the possible risk.
Use in Elderly: Salofalk should be used with caution in elderly patients.