Tablet: Adults: Acute Treatment: Ulcerative Colitis: 150-300 mg in divided dose 3 times a day. Crohn's Disease: 150-450 mg in divided dose 3 times a day. Maintenance Treatment: 500 mg tab 3 times a day. Use only in patients with normal kidney functions. Salofalk should be taken 1 hr before meals with plenty of fluid.
Granules: Adults and the elderly: For the treatment of acute episodes of ulcerative colitis: Once daily, 1-2 sachets of Salofalk 1.5 g granules, (equivalent to 1.5-3.0 g mesalazine daily) preferably to be taken in the morning according to the individual clinical requirement.
For the maintenance of remission of ulcerative colitis: The standard treatment is 0.5 g mesalazine three times daily (in the morning, at midday and in the evening) corresponding to a total dose of 1.5 g mesalazine per day.
For patients known to be at increased risk for relapse for medical reasons or due to difficulties to adhere to application of three daily doses, the dosing schedule can be adapted to 3.0 g mesalazine given as a single daily dose, preferably in the morning.
Suppository: one or two suppositories two to three times daily.
Enema: Unless otherwise prescribed by your doctor, the recommended dose for the treatment of acute episodes of ulcerative colitis is one enema a day to be used at bedtime.