Do not apply to area around nose, mouth, and mucous membrane.
Use with caution in pregnant and nursing women.
Topical application may cause some local erythema and peeling effect.
If local irritation develop, reduce the dosage or discontinue this medications until the skin has adapted to Tretinoin.
Use with caution in patients have acute eczema, because may occurs serious skin irritation.
During the use of this medications exposure to sunlight should be avoided, in patients who owning to their occupation are exposed to sunlight, the use of sunscreen and wear protective
clothing is recommended.
Patients with sunburn should be withdrawned from the medications until the skin has recovered.
Excessive application this medications may lead to marketed redness, peeling or discomfort.