Do not apply to area around nose, mouth, & mucous membrane. May cause some local erythema & peeling effect. Reduce the dosage or discontinue use if local irritation develop. Serious skin irritation may occur in patients w/ acute eczema. Avoid exposure to sunlight during treatment. Use sunscreen & wear protective clothing is recommended. Patients w/ sunburn should be withdrawned from the medication. Excessive application may lead to marketed redness, peeling or discomfort. Pregnant & nursing women.