Each film-coated tablet contains: Ondansetron hydrochloride dihydrate equivalent to Ondansetron 4 mg.
Pharmacology: Ondansetron is a highly selective and competitive 5HT3 receptor antagonist, which inhibits nausea and vomiting caused by cytotoxic agents and radiation.
For oral: The management of nausea and vomiting associated with the treatment of cancer by chemotherapy and radiotherapy and for prevention of post-operative nausea and/or vomiting.
For prevention of post-operative nausea vomiting: Initial dose: 8 mg tablet, given 1 hour before anaesthesia, followed by 8 mg tablet every 8 hours for up to 16 hours.
For nausea and vomiting of radiotherapy: 8 mg tablet 8 hourly commencing 1-2 hours prior to the first fraction of radiotherapy. The course of the therapy depend on the duration of radiotherapy.
Elderly: Ondansetron is well tolerated by patients over 65 years and no alteration of dosage, dosing frequency or route of administration are required.
Patients with renal impairment: No alteration of daily dosage or frequency of dosing, or route of administration.
Patients with hepatic impairment: In such patients a total daily dose of 8 mg should not be exceeded.
Ondansetron is contraindicated for patients known to have hypersensitivity to the drug.
Ondansetron should not be used during pregnancy especially during the first trimester, unless the expected benefit to the patient is thought to outweigh any possible risk to the fetus. Test have shown that Ondansetron is excreted in the breast milk of rats. It is therefore recommended that mothers receiving Ondansetron should not breast feed their babies.
Ondansetron should not be used during pregnancy especially during the first trimester, unless the expected benefit to the patient is thought to outweigh any possible risk to the fetus. Test have shown that Ondansetron is excreted in the breast milk of rats. It is therefore recommended that mothers receiving Ondansetron should not breast feed their babies.
Headache, constipation, hot flushing in the head and epigastria, sedation and diarrhea.
Store at temperature below 30°C.
A04AA01 - ondansetron ; Belongs to the class of serotonin (5HT3) antagonists. Used for the prevention of nausea and vomiting.
Ondavar FC tab 4 mg
1 × 10's (Rp105,000/boks)
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