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For prevention of post-operative nausea vomiting: Initial dose: 8 mg tablet, given 1 hour before anaesthesia, followed by 8 mg tablet every 8 hours for up to 16 hours.
For nausea and vomiting of radiotherapy: 8 mg tablet 8 hourly commencing 1-2 hours prior to the first fraction of radiotherapy. The course of the therapy depend on the duration of radiotherapy.
Elderly: Ondansetron is well tolerated by patients over 65 years and no alteration of dosage, dosing frequency or route of administration are required.
Patients with renal impairment: No alteration of daily dosage or frequency of dosing, or route of administration.
Patients with hepatic impairment: In such patients a total daily dose of 8 mg should not be exceeded.
