Ondacap Dosage/Direction for Use

Treatment of Postoperative Nausea and Vomiting: ONDACAP Injection 4 mg as single dose by i.m. or slow i.v. injection.
Prevention of Nausea and Vomiting Associated with Chemotherapy and Radiotherapy: Adult: Highly emetogenic chemotherapy, such as Cisplatin. Initially administer ONDACAP Injection 8 mg i.v. slowly or given as infusion for 15 minutes immediately before the start of chemotherapy, followed by continuous infusion of Ondansetron 1 mg/hour for less than 24 hours or 2 of ONDACAP Injection 8 mg administered by i.v. slowly or as infusion for 15 minutes with time interval 4 hours. Also could be followed by 8 mg orally twice daily for less than 5 days.
Moderately Emetogenic Chemotherapy, such as Cyclosphamide. ONDACAP Injection 8 mg administered i.v. slowly or as infusion for 15 minutes immediately before the start of chemotherapy, followed by 8 mg orally twice daily for less than 5 days.
Children older than 4 years: 5 mg/m² by i.v. over 15 minutes immediately prior to chemotherapy, followed by 4 mg orally every 12 Hours for up to 5 days.
Geriatric: ONDACAP is well tolerated by patients > 65 years and no need alterations of daily dose, frequency or route of administration.
Patient with Impaired Renal Function: No need alterations of daily dose, frequency or route of administration.
Patient with Impaired Hepatic Function: Total daily dose of 8 mg should not be exceeded.