Treatment of post-op nausea & vomiting 4 mg single dose by IM or slow IV inj.
Prevention of nausea & vomiting associated w/ chemotherapy & radiotherapy Highly emetogenic chemotherapy eg, cisplatin: Initially 8 mg slow IV or infusion for 15 min immediately prior to chemotherapy, followed by ondansetron 1 mg/hr continuous infusion for <24 hr or 2 inj of 8 mg by slow IV or infusion for 15 min w/ 4 hr interval. Also could be followed by 8 mg orally twice daily for <5 days. Moderately emetogenic chemotherapy eg, cyclosphamide: 8 mg by slow IV inj or infusion for 15 min immediately prior to chemotherapy, followed by 8 mg orally twice daily for <5 days.
Childn >4 yr 5 mg/m
2 IV over 15 min immediately prior to chemotherapy, followed by 4 mg orally every 12 hr for up to 5 days.
Patient w/ impaired hepatic function Max: 8 mg.
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