Kenacort Dosage/Direction for Use

The initial dosage of Kenacort tablets may vary from 4-48 mg/day depending on the specific disease entity being treated. In situations of lesser severity, lower doses will generally suffice while in selected patients, higher initial doses may be required. The initial dosage should be maintained or adjusted until a satisfactory response is noted. If after a reasonable period of time there is lack of satisfactory clinical response, the corticosteroid should be discontinued and the patient transferred to other appropriate therapy. It should be emphasized that dosage requirements are variable and must be individualized on the basis of the disease under treatment and the response of the patient.
For infants and children, the recommended dosage should be governed by the same considerations rather than by strict adherence to the ratio indicated by age or body weight. After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small increments at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached. It should be kept in mind that constant monitoring is needed in regard to drug dosage. Changes in dose may be necessary if the clinical status changes, the patient's individual responsiveness changes or the patient is exposed to stressful situation not directly related to disease under treatment; it may be necessary to increase the dosage of the Kenacort for a period of time consistent with the patient's condition. If after long-term therapy Kenacort is to be stopped, it is recommended that Kenacort be withdrawn gradually rather than abruptly.
Hormone therapy is an adjunct to, and not a replacement for, conventional therapy.
To Transfer Patients from Other Corticosteroids: Substitute Kenacort 4 mg initially in place of each cortisone 25 mg, hydrocortisone 20 mg, prednisone 5 mg, prednisolone 5 mg, methylprednisolone 4 mg, dexamethasone 0.75 mg, betamethasone 0.6 mg and paramethasone 2 mg. Thereafter, dosage should be adjusted according to individual response.