Na & fluid retention, CHF, K loss, hypokalemia alkalosis, HTN; muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis (femoral & humeral heads), pathologic & spontaneous fractures; peptic ulcer; impaired wound healing, thin fragile skin, petechiae & ecchymoses, facial erythema, increased sweating, SC fat atrophy, purpura, striae, hyperpigmentation, hirsutism, acneform eruptions & suppressed reactions to skin test; convulsion, increased ICP, vertigo, headache, neuritis or paresthesia, aggravation of preexisting psychiatric conditions; menstrual irregularities, development of Cushingoid state, suppression of growth in childn, secondary adrenocortical & pituitary unresponsiveness (trauma, surgery, illness), decreased carbohydrate tolerance, manifestation of DM; posterior subcapsular cataracts; glaucoma, exophthalmos; hyperglycemia, glycosuria, -ve nitrogen balance; necrotizing angiitis, thrombophlebitis, aggravation or masking of infections, insomia, syncopal episodes, anaphylactoid reactions.