Kenacort Adverse Reactions

Patients should be watched closely for the following adverse reactions which may be associated with any corticosteroid therapy:
Fluid and Electrolyte Disturbance: Sodium retention, fluid retention, congestive heart failure in susceptible patients, potassium loss, hypokalemic alkalosis and hypertension.
Musculoskeletal: Muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis of femoral and humeral heads, pathologic fractures of long bones and spontaneous fractures.
Gastrointestinal: Peptic ulcer with possible subsequent perforation and hemorrhage, pancreatitis, abdominal distention and ulcerative esophagitis.
Dermatologic: Impaired wound healing, thin fragile skin, petechiae and ecchymoses, facial erythema, increased sweating, subcutaneous fat atrophy, purpura, striae, hyperpigmentation, hirsutism, acneform eruptions and suppressed reactions to skin tests.
Neurological: Convulsions, increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment, vertigo, headache, neuritis or paresthesias and aggravation of preexisting psychiatric conditions.
Endocrine: Menstrual irregularities; development of the Cushingoid state; suppression of growth in children; secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress (eg, trauma, surgery or illness); decreased carbohydrate tolerance; manifestations of diabetes mellitus from a previously latent state and increased requirements for insulin or oral hypoglycemic agents in diabetes.
Ophthalmic: Posterior subcapsular cataracts, increased intraocular pressure, glaucoma and exophthalmos.
Metabolic: Hyperglycemia, glycosuria and negative nitrogen balance due to protein catabolism.
Others: Necrotizing angiitis, thrombophlebitis, aggravation or masking of infections, insomnia, syncopal episodes and anaphylactoid reactions.