Fluxar Dosage/Direction for Use

Cryptococcal meningitis: Usual dose for adults: 400 mg as a single dose on the first day followed by 200-400 mg daily. Duration of treatment for cryptococcal infections will depend on the clinical and mycological response (usually at least 6-8 weeks). In patients with AIDS, fluconazole may be administered indefinitely at a once daily dose of 200 mg.
Systemic candidiasis: Usual dose for adults: 400 mg as a single dose on the first day followed by 200 mg daily. Depending on the clinical response, the dose may be increased to 400 mg daily. Duration of treatment is based upon the clinical response.
Oropharyngeal candidiasis: Usual dose for adults: 50 mg once daily for 1-2 weeks. If necessary, treatment can be continued for maintenance. This dose is the same for esophagus candidiasis however the period of therapy takes longer (approximately 14-30 days). Maximum dose is 100 mg.
Acute vaginal candidiasis or relapse: Usual dose for adults: 150 mg as a single dose.
Use in children: use in children <16 years is not recommended, however when the treating physician considers fluconazole therapy imperative the following: Children ≥1 year with normal renal function are recommended: 1-2 mg/Kg body weight daily for superficial candidal infections and 3-6 mg/Kg body weight for systemic candidal/cryptococcal infections. Daily doses up to 12 mg/Kg body weight have been used in a small number of children provided not exceeding 400 mg/day.
Use in geriatric patients: When there is no evidence of renal impairment, normal dosage recommendations should be adopted. For patients with renal impairment (creatinine clearance <50 mL/min), the dosage schedule should be adjusted.