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Phenytoin, Phenobarbital, and Carbamazepine increasing the elimination half-life of Doxycycline, possibly decreasing Doxycycline level in blood.
Absorption of drugs of the tetracycline class per oral impaired if given with milk or Ca, Al, Mg, Fe minerals.
Oral contraceptives: Doxycycline can reduce the effectivity of oral contraceptives.
