Tysabri Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Speak to the doctor or nurse immediately if the patient notices any of the following: Symptoms of serious infections including: An unexplained fever, Severe diarrhea, Shortness of breath, Prolonged dizziness, Headache, Weight loss, Listlessness.
A group of symptoms caused by a serious infection of the brain including: Changes in personality and behaviour such as confusion, delirium or loss of consciousness, seizures (fits), headache, nausea/vomiting, stiff neck, extreme sensitivity to bright light, fever, rash (anywhere on the body).
These symptoms may be caused by an infection of the brain (encephalitis) or its covering layer (meningitis).
Signs of allergy to TYSABRI, during or shortly after the infusion: Itchy rash (hives); Swelling of the face, lips or tongue; Difficulty breathing; Chest pain or discomfort; Increase or decrease in the blood pressure (the doctor or nurse will notice this if they are monitoring the blood pressure).
Signs of a possible liver problem: Yellowing of the skin or the whites of the eyes; Unusual darkening of the urine.
TYSABRI can also have other side effects: Side effects are listed as follows by how commonly they have been reported in clinical trials: Common side effects that may affect up to 1 in 10 people: Urinary tract infection, Sore throat and runny or blocked up nose, Shivering, Itchy rash (hives), Headache, Dizziness, Feeling sick (nausea), Being sick (vomiting), Joint pain, Fever, Tiredness.
Uncommon side effects that may affect up to 1 in 100 people: Severe allergy (hypersensitivity), Progressive multifocal leukoencephalopathy (PML).
Rare side effects that may affect up to 1 in 1,000 people: Unusual infections (so-called "Opportunistic infections"), Severe anaemia (decrease in the red blood cells which can make the skin pale and can make the patient feel breathless or lacking energy).
Speak to the doctor as soon as possible if the patient thinks he/she has an infection.
Show the Alert Card and package leaflet to any doctor involved with the treatment, not only to the neurologist.
The patient will also find this information in the Patient Alert Card given by the doctor.