Dormicum Adverse Reactions

Ampoule: Dormicum is well tolerated. Slight decrease in arterial blood pressure and slight changes of heart rate and respiration are fairly common.
Severe cardiorespiratory adverse events have occurred on rare occasions. These have included respiratory depression, apnea, respiratory arrest and/or cardiac arrest.
Such life-threatening incidents are more likely to occur in adults >60 years and those with preexisting respiratory insufficiency or impaired cardiac function, particularly when the injection is given too rapidly or when a high dosage is administered. Dormicum should be used only when resuscitation facilities are available.
The following adverse events have also been observed: Nausea, vomiting, headache, hiccups, laryngospasm, dyspnea, hallucination, oversedation, drowsiness and ataxia. Anterograde amnesia may still be present at the end of the procedure and in isolated cases, prolonged amnesia has been reported.
In rare cases, paradoxical reactions eg, agitation, hyperactivity and aggressiveness have occurred; involuntary movements (including tonic/clonic convulsions and muscle tremor) have also been observed.
Local effects on veins (pain on injection and thrombophlebitis) can occur.
In isolated cases, generalized hypersensitivity, from skin reactions to anaphylactoid reactions, have been reported. Convulsions have been reported in premature infants and neonates.
After prolonged IV administration of Dormicum, abrupt discontinuation of the product may be accompanied by withdrawal symptoms.
After rectal administration, a slight euphoria has been observed.