Đăng xuất
If there are reports of hyperglycaemia in patients treated with atypical antipsychotic agents, the blood glucose of patients with diagnosed diabetes mellitus or with risk factors for having diabetes, who have started treatment with sulpiride, should be appropriately monitored.
Neuroleptics, including sulpiride, may reduce the seizure threshold, and some cases of seizures have been reported with sulpiride (see Adverse Reactions). Therefore patients with epilepsy or with a history of seizures should be strictly monitored during treatment with sulpiride.
Sulpiride is eliminated via the kidneys. In case of kidney failure, the dose should be reduced (see Dosage & Administration).
Like other neuroleptics, sulpiride should be used with caution in elderly patients since they may be at a higher risk of developing orthostatic hypotension, sedation and extrapyramidal disorders such as tardive dyskinesia. Observation is recommended during treatment to detect early signs of tardive dyskinesia, and reduce or discontinue treatment to prevent a more serious manifestation of the symptom. It is also advisable to monitor heart function.
Elderly patients may need a lower starting dose and a gradual adjustment of the dose (see Dosage & Administration).
In patients with aggressive behaviour or who are impetuously agitated, sulpiride can be administered with a sedative.
Warning about excipients: This medicinal product contains lactose. Patients with hereditary galactose intolerance, Lapp lactase deficiency (deficiency observed in some parts of Lapland) or glucose-galactose malabsorption should not take this medicinal product.
Effects on ability to drive and use machines: Even when used in accordance with recommendations, sulpiride may cause sedation, and the ability to drive or operate machines may be affected (see Adverse Reactions).
