Pregnancy: There are no or limited data from the use of caspofungin in pregnant women. CANCIDAS should not be used during pregnancy unless clearly necessary. Animal studies have shown developmental toxicity. Caspofungin has been shown to cross the placental barrier in animal studies.
Nursing Mothers: It is not known whether caspofungin is excreted in human milk. Available pharmacodynamic/toxicological data in animals have shown excretion of caspofungin in milk. Women receiving CANCIDAS should not breast feed.
Fertility: For caspofungin, there were no effects on fertility in studies conducted in male and female rats. There are no clinical data for caspofungin to assess its impact on fertility.