Đăng xuất
Follow the doctor's instructions.
Adults: The following gradually increasing dosage regimen is suggested, but should be adjusted to suit individual patient requirements: 5mg three times daily for 3 days.
10mg three times daily for 3 days.
15mg three times daily for 3 days.
20mg three times daily for 3 days.
Satisfactory control of symptoms is usually obtained of up to 60mg daily, a careful adjustment is often necessary to meet the requirements of each individual patient. The dose may be increased slowly if required, but a maximum dose of 100mg is not advised unless the patient is in hospital under medical supervision.
Small frequent dosage may prove better in some cases than large doses. Also, some patients may benefit from the use of Bamifen at night to counteract painful flexor spasm. Similarly, a single dose given approximately 1 hour prior to performance of specific tasks (washing, dressing, shaving, physiotherapy) will often improve mobility.
Once the maximum recommended dose has been reached, if the therapeutic effect is not apparent within 6 weeks, a decision whether to continue Bamifen should be taken.
Elderly: Small doses should be used at the start of the treatment and the dose being titrated gradually against the response, under careful supervision.
Children: A dosage range of 0.75 - 2 mg / kg body weight should be used. In children over 10 years of age, a maximum daily dosage of 2.5mg / kg body weight may be given. Treatment is usually started with 2.5mg four times daily. The dosage should be cautiously raised at about 3 day intervals, until it becomes sufficient for the child's individual requirements. The recommended daily maintenance dose is: Children 12 months - 2 years: 10 - 20 mg.
Children 2 years - 6 years: 20 - 30 mg.
Children 6 years - 10 years: 30 - 60mg.
Patients with impaired renal function: It is recommended a low dose, e.g. 5mg daily.
Patients with spastic states of cerebral origin: Unwanted effects are more likely to occur at these patients. It is therefore recommended that a very cautious dosage schedule be adopted and that patients be kept under appropriate surveillance.
If the patient takes a dose larger than normal: In case the patient takes a dose larger than normal, stop taking the medicine and contact the doctor immediately.
Symptoms of overdosage: Symptoms from the Central Nervous System: Drowsiness, confusion, reduced reflexes, difficulty in breathing, hypotension, speech disturbance, general hypotonia and coma. It is also possible that the following may appear: hallucinations, bradycardia, hypothermia, nausea, vomiting, diarrhoea, high values of LDH, SGOT and AP.
Treatment: There is no special antidote for treating overdoses of Baclofen. General supportive measures such as stomach lavage, active charcoal and liquids administration as well as diuretic administration can be used.
If the patient forgets to take Bamifen: If the patient has to take this medicine continuously and they missed a dose they should take this dose as soon as possible. If the patient is close to the time of their next dose, do not take the missed dose but go back to the regular dosing schedule. Do not double doses. Consult the doctor in case the patient missed more than one dose.
