Zyller Dosage/Direction for Use

General recommendation: Levocetirizine is given once daily. Age-based recommended daily doses of levocetirizine are as following: Adults and Children 12 years of age and older: 5 mg daily. A dosage of 2.5 mg once daily may be adequate for some patients.
Children 6-11 years of age: 2.5 mg daily.
Dosage Adjustment in Renal Impairment: The clearance of levocetirizine is decreased in patients with renal impairment and dosage adjustment in these patients is required. Dosage of levocetirizine in adults and children 12 years of age and older should be based on the degree of renal impairment as shown in following table. Use of levocetirizine is contraindicated in children younger than 12 years old with renal impairment. (See Table.)

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Dosage Adjustment in Hepatic Impairment: Dosage adjustment is not necessary in patients with hepatic impairment.
Administration: Levocetirizine is orally administered once daily in the evening without regard to meals. The tablets of levocetirizine is scored and can be divided in half. Each half provides 2.5 mg of levocetirizine.