Treatment of moderate to severe hypercalcemia of malignancy (HCM). Osteolytic, osteoblastic & mixed bone metastases of solid tumors & osteolytic lesion of multiple myeloma in conjunction w/ standard antineoplastic therapy. Reduction of bone damage in patients w/ advanced bone malignancies.
Not to be mixed w/ Ca or other divalent cation-containing infusion soln eg, lactated Ringer's. Aminoglycosides, loop diuretics, nephrotoxic drugs, thalidomide.