Reduced requirement w/ antidiabetics, MAOIs, β-blockers, ACE inhibitors, salicylates, anabolic steroids, sulfonamides. Increased requirement w/ OCs, thiazides, glucocorticoids, thyroid & growth hormones, sympathomimetics, danazol. Masked hypoglycaemic symptoms w/ β-blockers. Increased or decreased requirement w/ octreotide/lanreotide. Intensified or reduced hypoglycaemic effect w/ alcohol. Reduced AUC & C
max of digoxin; lisinopril. Lowered C
max of ethinylestradiol & levonorgestrel.