Not to inj via IV or IM. Anaphylaxis & anaphylactoid reactions; serum sickness & serum sickness-like reactions. Known history of anaphylaxis. Not to be used for acute asthma exacerbations, acute bronchospasm or status asthmaticus. Atopic dermatitis, allergic rhinitis or food allergy. Patients at high risk of helminth infection; w/ hyper-IgE syndrome or allergic bronchopulmonary aspergillosis; autoimmune diseases, immune complex-mediated conditions. Women w/ poorly or moderately controlled asthma. Not recommended to abruptly discontinue systemic or inhaled corticosteroids after initiation of therapy in allergic asthma or nasal polyps. Pre-existing renal or hepatic impairment. Increased risk of pre-eclampsia in mother & prematurity, low birth wt, & small for gestational age in neonate. Closely monitor asthma level in pregnant women. Pregnancy & lactation. Not recommended in childn <6 yr w/ allergic asthma, <12 yr w/ CSU or <18 yr w/ nasal polyps. Elderly ≥65 yr.
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