IV infusion Administer as a 60-min IV infusion. Recommended dose: 60 u/kg administered every other wk. Dose adjustments can be made on an individual basis based on achievement & maintenance of therapeutic goals. Clinical studies have evaluated doses ranging from 15-60 u/kg every other wk.
Discontinue immediately if anaphylactic or other acute reactions occur. Hypersensitivity reactions, including symptoms consistent w/ anaphylaxis. Infusion-related reactions. Pre-treatment w/ antihistamines &/or corticosteroids to prevent subsequent reactions. Recommended max daily intake of 2 g for adult. Perform test for presence of Ab in cases of severe infusion-related reactions. Women of childbearing potential. Pregnancy. Discontinue lactation during treatment or discontinue/abstain from use during lactation. Childn <4 yr.
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