Patients w/ liver disease, co-infected w/ HIV, HBV, HCV or hepatitis D. Monitor kidney function prior to initiation of & during therapy. Discontinuation of therapy may result in exacerbation of hepatitis B. Perform regular health checks & blood test for several mth after discontinuation. Lactose intolerance or intolerance to other sugars. Do not drive or use tools or machines. Pregnancy & lactation. Childn <12 yr or weighing <35 kg.