Dissolution of cholesterol gallstone 8-10 mg/kg daily in 2-3 divided doses. Treatment duration: 6 mth to 2 yr of continuous dosing depending on size & composition of the stones. Monitor response by ultrasonograms performed at 6-mth interval during 1st yr of therapy. Continued for at least 3 mth after complete dissolution to promote dissolution of particles that are too small to image. Prevention of gallstone formation 300 mg bid.
Discontinue therapy if non-visualizing gallbladder develops. Patient who have undergone cholecystectomy. Long-term use (>24 mth). Not to be used during pregnancy. Lactation.
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