IM Inj into deltoid region of upper arm in adult, adolescent & childn; anterolateral thigh in infant. Primary vaccination schedule: Adult & adolescent ≥16 yr 3 doses: 1st dose at elected date, 2nd dose 1 mth later & 3rd dose 6 mth after 1st dose. If insufficient time is available to complete 0, 1, 6 mth schedule when travel is anticipated w/in ≥1 mth after initiating vaccination course, use 3 inj schedule at 0, 7 & 21 days + 4th dose at 12 mth after 1st dose. Childn & adolescent 1-15 yr 2 doses: 1st dose at elected date & 2nd dose between 6 & 12 mth after 1st dose. Booster dose: General guidelines can be drawn from experience w/ monovalent vaccines.
Rare anaphylactic event. Postpone vaccination in patients suffering from acute severe febrile illness. Not to be administered intravascularly. Not for preventing hepatitis C & E infection, & other pathogens known to infect liver. Not recommended for post-exposure prophylaxis eg, needle stick injury. Syncope (fainting). May not prevent hepatitis A or B in patients in incubation period. Patients on haemodialysis & w/ impaired immune system. Pregnancy & lactation.
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