Discontinue use if pancreatitis is suspected & not to be restarted if pancreatitis is confirmed. Not to be administered IV or IM. Not to be used in patients w/ type 1 DM or for treatment of diabetic ketoacidosis. Not a substitute for insulin. Not recommended for patients w/ severe GI disease including severe gastroparesis. Dehydration; acute pancreatitis; increased risk of hypoglycaemia. Patients w/ CHF. Monitor patients w/ history of diabetic retinopathy for progression. May cause deterioration of renal function including acute renal failure in patients w/ impaired renal function. May affect ability to drive or use machines when used in combination w/ sulphonylurea or insulin. Not recommended in patients w/ ESRD (estimated GFR <15 mL/min/1.73 m
2). Not recommended during pregnancy. Not to be used during lactation. Childn <18 yr.