Adjunct to diet in combination w/ statin reduce triglycerides & increase in HDL-C in patients w/ mixed dyslipidemia & CHD or a CHD risk equivalent (other clinical forms of atherosclerotic disease: Peripheral arterial disease, abdominal aortic aneurysm & symptomatic carotid artery disease, diabetes, multiple risk factors that confer a 10-yr risk for CHD >20%) who are on optimal statin therapy to achieve their LDL-C goal. Reduce triglycerides in patients w/ severe hypertriglyceridemia. Reduce elevated LDL-C, total cholesterol, triglycerides & Apo B & increase HDL-C in patients w/ primary hyperlipidemia or mixed dyslipidemia.
View Trilipix overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Swallow whole, do not open/chew/crush/dissolve.
Contraindications
Hypersensitivity to fenofibrate. Gallbladder disease; chronic or acute pancreatitis w/ the exception of acute pancreatitis due to severe hypertriglyceridemia; known phototoxic reaction during therapy w/ fibrates or ketoprofen. Severe renal insufficiency (CrCl <30 mL/min). Liver disease (including biliary cirrhosis & unexplained persistent liver function abnormality) & hepatic insufficiency.
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