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Based on the Ministry of Public Health's Announcement: 1. Contraindicated in patients with known hypersensitivity to any component of this product, pregnancy and lactation.
2. Contraindicated in patients who have recently undergone coronary artery bypass graft surgery.
3. Contraindicated in patients with cardiovascular or cerebrovascular disease.
4. Contraindicated in patients with un-controlled hypertension.
5. Contraindicated in patients with myocardial infarction or congestive heart failure NYHA II-IV.
6. Contraindicated in patients with history of ischemic heart disease or history of paralysis from cerebrovascular disease.
7. Caution should be used in patients with risk factors for cardiovascular events e.g. hypertension, hyperlipidemia, diabetes mellitus, smoking, elderly.
8. Caution should be used in patients with liver or renal disease.
