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Etoricoxib should be used with caution in patients with significant risk factors for cardiovascular disease such as hypertension, hyperlipidaemia and diabetes mellitus.
Etoricoxib should be avoided in patients who have a history of mild allergic phenomena related to ingestion of other nonsteroidal anti-inflammatory drugs eg, rash.
Etoricoxib should be avoided in patients who have conditions predisposing to gastrointestinal events (eg, history of peptic ulcer, upper gastrointestinal disease, ulcerative colitis; smoking; advancing age; concurrent aspirin or corticosteroids; alcohol abuse; stress).
Etoricoxib should be avoided in patients with bleeding disorders (potential exacerbation).
