Adult & childn >12 yr 4.5 g 8 hrly. Total daily dose: 2.25-4.5 g 6-8 hrly. NeutropeniaAdult 4.5 g 6 hrly in combination w/ an aminoglycoside. Childn 90 mg/kg IV 6 hrly in combination w/ an aminoglycoside. Max: 4.5 g 6 hrly. Intra-abdominal infectionsChildn 2-12 yr >40 kg 4.5 g 8 hrly, up to 40 kg 112.5 mg/kg 8 hrly. To be given by slow IV infusion over 20-30 min or slow IV inj over at least 3-5 min.
Renal impairment, pregnancy & lactation. Periodic assessment of organ system functions including renal & hepatic, hematopoietic function & electrolyte determinations should be performed.
J01CR05 - piperacillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
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