Initially 200-400 mg daily in 2 divided doses, in 1 wk gradually increase to maintenance dose: 400 mg daily in 2 divided doses. May be increased to 800 mg daily or reduced to 200 mg daily.
View Sulfin overdosage for action to be taken in the event of an overdose.
Administration
Should be taken with food: Take w/ meals or milk.
Contraindications
History or presence of hypersensitivity to phenylbutazone or other pyrazoles; blood dyscrasias. Active peptic ulcer or symptoms of GI inflammation or ulceration.
History of healed peptic ulcer. May precipitate urolithiasis & renal colic. Not for acute gout. Ensure adequate fluid intake & urine alkalinization. Periodically monitor blood counts & assess renal function. Concomitant use w/ sulfa drugs, sulfonylurea hypoglycemic agents & insulin; coumarin-type anticoagulants; salicylates. Renal impairment. Not to be used in pregnancy & lactation.
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