Pregnancy: Pregnancy category: B.
Cimetidine can cross the placenta. An increased risk of congenital malformations or adverse event in the newborn has generally not been observed following maternal use of these agents during pregnancy. H2 antagonists may be used for aspiration prophylaxis prior to cesarean delivery. However, the use of Cimetidine during pregnancy should be avoided unless considered essential by the physician.
Lactation: Cimetidine is excreted in breast milk. The concentration of Cimetidine in maternal serum in comparison to breast milk is highly variable. Breast-feeding is not recommended unless considered essential by the physician.