Hypersensitivity to streptomycin &/or neomycin. Ovarian hyperstimulation syndrome (OHSS); arterial thromboembolism or VTE; transient LFTs. Ovarian torsion. Potential risk of multiple births prior to treatment. Increased risk of tumors in infertile women. Women w/ risk factors for high ovarian response; thromboembolic events eg, personal or family history, severe obesity or thrombophilia. Men w/ elevated endogenous FSH levels. Assess infertility & evaluate for hypothyroidism, adrenocortical insufficiency, hyperprolactinemia & pituitary or hypothalamic tumors prior to therapy. Monitor patients for at least 2 wk after HCG administration. Perform ultrasound assessments of follicular development prior to & at regular intervals during therapy. Evaluate medical conditions contraindicating pregnancy before starting treatment. Increased incidence of ectopic pregnancies in infertile women undergoing assisted reproductive technology. Lactation.
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